Executive Director, Global In-Line Brands & Global Commercial Execution

Company: Amgen
Location: Thousand Oaks
Posted on: January 31, 2026

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Live What you will do Lets do this. Lets change the world. In this vital role, the Executive Director, Global In-Line Brands & Global Commercial Execution will provide enterprise-level commercial leadership for a cross-therapeutic portfolio of mature, in-line assets, ensuring sustained value creation through disciplined global strategy, strong market pull-through, and continuous improvement of Amgens global-with-local operating model.This role is accountable for maximizing the lifecycle value of assigned brands, shaping global brand strategy in partnership with markets, and ensuring executional excellence, consistency, and focus across regions. Please note 25% international travel is likely. Primary Responsibilities: Portfolio & Brand Leadership Provides commercial leadership across a portfolio of global in-line brands (e.g., Otezla, Prolia, Kyprolis, Nplate, Xgeva, Vectibix) through the full lifecycle Maximizes asset value by guiding brand strategy, prioritization, and investment decisions, including any remaining Patient Impact Expansion (PIE) opportunities Ensures clear global brand positioning and strategic coherence across therapeutic areas and markets Global-With-Local Operating Model Oversees and optimizes the global-with-local commercial execution model, ensuring strong connectivity between global strategy and local execution Partners closely with key markets to co-create brand strategies, balancing global consistency with local market needs Drives focus on the highest-value opportunities and ensure resources are deployed against clear commercial priorities Commercial Execution & Cross-Functional Leadership Leads and influences cross-functional partners across Global Commercial Operations, regions, and therapeutic areas to deliver aligned commercial plans Serves as a key commercial voice in global governance forums, ensuring timely, high-quality commercial input to decision-making Champions best practices, continuous improvement, and disciplined execution across global commercial activities People & Team Leadership Leads and develops a high-impact global team, including: In-Line Global Marketing Directors, accountable for global brand strategy and planning Global Commercial Execution Leads (GCELs) aligned by therapeutic area, accountable for market pull-through and executional excellence Sets clear expectations, fosters collaboration, and builds strong succession and capability pipelines Enterprise Influence Partners with Global Marketing Therapeutic Area VPs to continuously evolve ways of working and strengthen global-local collaboration Builds strong relationships across functions and geographies, influencing without authority in a complex matrix environment Acts as a role model for Amgen leadership behaviors and values What we expect of you We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a leader with these qualifications. Basic Qualifications: Doctorate degree and 6 years of global commercial or marketing experience OR Masters degree and 10 years of global commercial or marketing experience OR Bachelors degree and 12 years of global commercial or marketing experience AND 6 years of managerial experience leading people, teams, programs, or enterprise initiatives Preferred Qualifications: Experience leading global commercial or marketing teams in the biopharmaceutical industry Success managing mature, in-line brands and optimizing lifecycle value Understanding of global-with-local operating models and executional governance Ability to influence senior stakeholders and drive alignment across regions and functions Experience working across multiple therapeutic areas and competitive markets Brings business judgment, prioritization skills, and executive presence MBA or equivalent advanced business training preferred What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.The annual base salary range for this opportunity in the U.S. is $315,211 to $362,906. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans and bi-annual company-wide shutdowns Flexible work models, including remote work arrangements, where possible As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship for this role is not guaranteed.

Keywords: Amgen, Santa Barbara , Executive Director, Global In-Line Brands & Global Commercial Execution, PR / Public Relations , Thousand Oaks, California